Difference between revisions of "Supramolecular Assembly of Biological Molecules Purified from Bovine Nerve Cells: from Microtubule Bundles and Necklaces to Neurofilament Networks"
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− | Needleman et al. examine the behavior of neurofilaments (NFs) <i>in vitro</i> in solutions containing different polyelectrolytes (i.e., in different salt solutions). In short, they found that the NFs formed hexagonal bundles in solutions with containing cations with a greater charge and larger size, while the NFs formed what the authors term "living necklace bundles" in solutions containing bivalent cations (Figure 1). | + | Needleman et al. examine the behavior of neurofilaments (NFs) <i>in vitro</i> in solutions containing different polyelectrolytes (i.e., in different salt solutions). In short, they found that the NFs formed hexagonal bundles in solutions with containing cations with a greater charge and larger size, while the NFs formed what the authors term "living necklace bundles" in solutions containing bivalent cations (Figure 1). The authors go on to quantify this bundling via scattering experiments, although optical and electron micrographs seem to sufficiently reveal the bundling behaviors. |
Revision as of 02:25, 18 March 2009
Zach Wissner-Gross (March 16, 2009)
Information
Supramolecular assembly of biological molecules purified from bovine nerve cells: from microtubule bundles and necklaces to neurofilament networks
Daniel J. Needleman, Janya B. Jones, Uri Raviv, Miguel A. Ojeda-Lopez, H. P. Miller, Y. Li, L. Wilson, and C. R. Safinya
Journal of Physics: Condensed Matter, 2005, 17, S3225-S3230
Soft matter keywords
Self-assembly, packing structure
Summary
Needleman et al. examine the behavior of neurofilaments (NFs) in vitro in solutions containing different polyelectrolytes (i.e., in different salt solutions). In short, they found that the NFs formed hexagonal bundles in solutions with containing cations with a greater charge and larger size, while the NFs formed what the authors term "living necklace bundles" in solutions containing bivalent cations (Figure 1). The authors go on to quantify this bundling via scattering experiments, although optical and electron micrographs seem to sufficiently reveal the bundling behaviors.