Reversible aggregation of responsive polymer-stabilized colloids and the pH-dependent formation of porous scaffolds
Entry by Pichet Adstamongkonkul, AP 225, Fall 2011
Work in progress
Title: Reversible aggregation of responsive polymer-stabilized colloids and the pH-dependent formation of porous scaffolds
Authors: Robert T. Woodward, Christopher Hight, Ufuk Yildiz, Nicolas Schaeffer, Esther M. Valliant, Julian R. Jones, Molly M. Stevens, and Jonathan V. M. Weaver
Journal: Soft Matter, 2011, Vol. 7, No. 16
Fine tuning interactions of colloids, such as switching the properties in response to stimuli and on-demand disassembly, is a very interesting aspect in the field and can have many applications. An alternative strategy of polymeric particles synthesis, in contrast with the in situ syntheses in poor solvent or self-assembly, is the isolation of pre-formed polymer within localized microscopic domains and template removal of solvent to form colloids, the so-called emulsion-solvent-evaporation (ESE) process. In this process, surfactant molecules play an important part in stabilizing the initial emulsion templates. In this study, the authors synthesized a pH-responsive, branched, amphiphilic copolymers of hydrophilic poly(ethylene glycol) methacrylate (PEGMA) and poly(methacrylic acid) (PMA), and 1-dodecanethiol-derived (DDT) hydrophobic chain ends.