Millimeter-Scale Contact Printing of Aqueous Solutions using a Stamp Made out of Paper and Tape

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The Whitesides lab has devoted great effort to develop paper-based microfluidic technology. Previous work adapted a commercial printer to achieve micro-scale resolution and accurate reagent delivery, the present paper demonstrates printing with using a low cost, easy-to-assemble device. The technology is equipped to deliver aqueous reagents with millimeter scale resolution. Applications include low cost medical diagnostic devices.

Materials and Methods

Devices were assembled with layers of patterned paper attached by layers of double-sided tape. "Ink", aka, the reagents of interest, flows from the rechargeable reservoir in the bottom paper layer. The ink then wicks through the sequence of paper layers, finally assuming the desired pattern atop the stamp. Printing is achieved by pressing the stamp to a fresh substrate, delivering the desired reagents. Figure 1 shows the layout of an example device.

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