Microoxen: Microorganisms to Move Microscale Loads.
"Microoxen: Microorganisms to Move Microscale Loads"
Douglas B. Weibel, Piotr Garstecki, Declan Ryan, Willow R. DiLuzio, Michael Mayer, Jennifer E. Seto, & George M. Whitesides
PNAS 102(34) 11963-11967 (2005)
Soft Matter Keywords
algae, phototaxis, photochemistry, beast of burden
The authors detail a very novel approach to transporting small payloads using biological motors. Instead of attaching synthesized motors to a load, Weibel, et al. attach the load to an organism. This allows them to steer the transport of the load by controlling the locomotion of the organism. In this case, the unicellular photosynthetic algae Chlamydomonas reinhardtii was chosen for its robust locomotion and phototactic characteristics. The simulated loads in these experiments were surface modified polystyrene beads. The peptide used to attach the bead to the algae cell contained a photo-active group that allows the bead to be cleaved from the cell when exposed to UV light of the appropriate wavelength. In this way, the beads can be delivered to a particular location and then deposited.
Practical Application of Research
Moving Loads with Tiny Oxen
written by Donald Aubrecht