Prepared by Max Darnell - AP225 Fall 2011
Lipids can be thought of as micelles with both inner and outer hydrophobic portions. These constructs are comprised of phospholipids which are ampipathic, meaning that they contain both hydrophilic and hydophobic regions. In aqueous solutions, these phospholipids self-assemble to shield their hydrophobic regions from the solvent. Lipososmes form when the "shell" consists of a double layer of lipids such that the interior is an aqueous solution as well. They were discovered in 1961.
Applications/Connections to Soft Matter
Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & And Walter, P. (2008). Molecular Biology of the Cell. (Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, & P. Walter, Eds.) Garland Press.