Geometrically Mediated Breakup of Drops in Microfluidic Devices
Zach Wissner-Gross (February 9, 2009)
Howard Stone and coworkers describe two techniques for breaking up droplets in an emulsion using microfluidic devices. The first method makes use of a "T-junction," in which a droplet flows down a channel that abruptly bifurcates into two channels in an orthogonal direction. The second method involves placing an obstacle in the droplet's path. Also notable is the article's analysis of the conditions under which a droplet encountering a T-junction will actually break up.
The process of creating droplets in the first place was previously described by Steve Quake and coworkers , who mixed two immiscible liquids in a similar T-junction microfluidic circuit, made from PDMS using soft lithography . Stone and coworkers used oil (hexadecane) and water to make the emulsion, including a surfactant to lower the surface tension between the two liquids in order to stabilize droplets.
Water droplets in the oil emulsion were flowed toward the T-junction, where they encountered a stagnation point at the intersection (Figure 1). Under certain conditions, the droplets would simply flow into one of the two side channels -- the authors mention that unbroken droplets in fact precisely alternate which channel they choose, although this phenomenon appears non-trivial to me. Perhaps when a given droplet selects one channel, it increases the fluidic resistance of that channel so that the next droplet favors the other channel. But more interestingly, under different conditions, oil flowing behind the droplet will pinch closed the surface, thus breaking the drop into two smaller droplets.