Difference between revisions of "From molecular noise to behavioral variability in a single bacterium"

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== Soft Matter Keywords ==
== Soft Matter Keywords ==
bacteria, chemotaxis, signaling pathway
bacteria, E. coli, chemotaxis, signaling pathway
[[Image:Korobkova-1.jpg|250px|thumb|right|Figure 1.  aslkjfsdklf]]
[[Image:Korobkova-1.jpg|250px|thumb|right|Figure 1.  aslkjfsdklf]]

Revision as of 17:51, 15 April 2009

"From molecular noise to behavioural variability in a single bacterium"
Ekaterina Korobkova, Thierry Emonet, Jose M.G. Vilar, Thomas S. Shimizu, & Philippe Cluzel
Nature 428 574-578 (2004)

Soft Matter Keywords

bacteria, E. coli, chemotaxis, signaling pathway

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The authors present primarily experimental work regarding a study of the chemotaxis network governing the motion of Escherichia coli. In the past, experiments and models for this system have assumed that network properties can be inferred from population measurements, which has the unfortunately effect of masking temporal fluctuations of intracellular signaling events. Korobkova, et al. study a noise analysis of behavioural variations in individual bacteria as a route to inferring fundamental properties of the chemotaxis network. They observe some properties established by population measurements to not be conserved at the single-cell level and find behaviour of non-stimulated bacteria displaying temporal variations much larger than expected statistical fluctuation. The authors have also found that the temporal behavioural variablity is strong dependent on the concentration of a key network component.

Practical Application of Research


Projectile Interaction with Foams


written by Donald Aubrecht