- Fluorinating a surface or applying a fluorinated coating lowers the surface energy and makes the surface more hydrophobic. Desbief et. al.  coat an aluminum surface with a fluorinated block copolymer to make the aluminum more hydrophobic.
- Many companies make fluorinated plastic containers which are less permeable than simple HDPE containers.
- Many common pharmaceuticals are fluorinated. Fluorinating pharmaceuticals makes them more lipophilic, enhancing absorption of the drug.
 Desbief, S., Grignard, B., Detrembleur, C., Rioboo, R., Vaillant, A., Seveno, D., Voue, M., De Coninck, J., Jonas, A.M., Jerome, C., Damman, P., and Lazzaroni, R. Superhydrophobic Aluminum Surfaces by Deposition of Micelles of Fluorinated Block Copolymers.Langmuir (2009). doi: 10.1021/la902565y.
 Ismail, F. Important Fluorinated Drugs in Experimental and Clinical Use. Journal of Fluorine Chemistry 118, 27-33 (2002).