Dynamic Pattern Formation in a Vesicle-Generating Microfluidic Device.

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Entry by Yuhang Jin, AP225 Fall 2011


Todd Thorsen, Richard W. Roberts, Frances H. Arnold, and Stephen R. Quake, Phys. Rev. Lett., 2001, 86, 4163.


pattern formation, emulsions, self-organization, microfluidics


This Letter presents a simple microfluidic device designed to generate ordered patterns. Viscous forces, especially those on the interface between two phases of flow, lead to the production of motifs from droplets to helices etc. The physics far from equilibrium is responsible for the mechanism of this pattern formation.

Experiments and results

Fig.1 The microfluidic structure for the production of emulsions.

Most microfluidic devices work at low Reynolds number, resulting in a laminar flow in the channels according to the Navier-Stokes equation, if only one fluid phase is involved. However, interaction between two immiscible fluids can give rise to complex pattern formation, which is an interesting example of self-organization out of equilibrium.

In this Letter, the authors design a device in which emulsions are formed by shearing one liquid into a second immiscible one. In this process, a proper concentration of surfactant is critical to reduce the surface energy and therefore facilitate the generation of droplets. The structure is shown in Fig. 1. High shear forces at the leading edge of the water perpendicular to the oil flow generate picoliter-scale droplets. This droplet formation is a result of competition between surface tension and shear forces.