Difference between revisions of "Bacillus subtilis spreads by surfing on waves of surfactant"
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In times of stress ''Bacillus subtilis''
In times of stress ''Bacillus subtilis'' a . ''B. Subtilis'' to -cannibal cellscannibal cellsthe of the spread in environmentto . .
Revision as of 15:06, 9 November 2009
currently being edited by Nikolai
Bacillus subtilis spreads by surfing on waves of surfactant
Angelini T.E., Roper M., Kolter R., Weitz D.A., Brenner M.P.
PNAS 106: 18109-18113 (2009) PMID: 19826092 (Pubget)
In times of stress Bacillus subtilis differentiate into spores, which helps them survive but at a significant energy cost. B. Subtilis try to keep this by three known mechanisms: 1) a sub-population of cells differentiations into cannibal cells, which selectively lyse non-cannibal cells; 2) the cells form a dense mat of exopolysacharides, called a biofilm; and 3) the cells spread out in search of a more hospitable environment. All three mechanisms appear to be controlled by the same regulatory protein, Spo0A. This protein is part of a quorum sensing system. The lipopetide surfactin secreted by the bacteria
A 'B. subtilis' biofilm is thicker in the center that at the edges. If we assumed that:
- Surfactin secreted by cells moves quickly to the air-biofilm interface.
- Surfactin reduces the film surface tension.
- All cells secrete surfactin at the same rate.
- The bacteria are homogeneously distributed throughout the film.
López D, Vlamakis H, Losick R, Kolter R., Cannibalism enhances biofilm development in Bacillus subtilis. Mol Microbiol (2009). Pubget