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Written by Yuhang Jin, AP225 2011 Fall.


"Amphiphilic" is used to describe the properties of a certain group of chemicals. A chemical substance being amphiphilic possesses both hydrophilic and lipophilic functional groups. As a result, amphiphilic compounds show good affinity for both water and oil, and have relatively high solubility in polar solvents like water and some non-polar solvents.

Structure and examples of amphiphilic molecules

In amphiphilic molecules, the hydrophilic group is usually charged and highly polar. Examples include carboxylates -RCO2- and sulfonates -SO3- with negative charges and amines -NH3+ with positive charges.

See also:

Amphiphilic in Surfactants from Lectures for AP225.

Keyword in references:

Amphiphilic Crescent-Moon-Shaped Microparticles Formed by Selective Adsorption of Colloids